CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
Superfamily | P-loop containing nucleotide triphosphate hydrolases |
Functional Family | Guanine nucleotide-binding protein G(i) subunit alpha-1 |
Enzyme Information
UniProtKB Entries (3)
P54311 |
GBB1_RAT
Rattus norvegicus
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
|
P63212 |
GBG2_BOVIN
Bos taurus
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
|
P63096 |
GNAI1_HUMAN
Homo sapiens
Guanine nucleotide-binding protein G(i) subunit alpha-1
|
PDB Structure
PDB | 5TDH |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
The structural basis of the dominant negative phenotype of the G alpha i1 beta 1 gamma 2 G203A/A326S heterotrimer
Acta Pharmacol.Sin.
|