CATH Classification

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Estrogen receptor

Enzyme Information

UniProtKB Entries (1)

P03372
ESR1_HUMAN
Homo sapiens
Estrogen receptor

PDB Structure

PDB 5T92
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of an Acrylic Acid Based Tetrahydroisoquinoline as an Orally Bioavailable Selective Estrogen Receptor Degrader for ER alpha + Breast Cancer.
Burks, H.E., Abrams, T., Kirby, C.A., Baird, J., Fekete, A., Hamann, L.G., Kim, S., Lombardo, F., Loo, A., Lubicka, D., Macchi, K., McDonnell, D.P., Mishina, Y., Norris, J.D., Nunez, J., Saran, C., Sun, Y., Thomsen, N.M., Wang, C., Wang, J., Peukert, S.
J. Med. Chem.
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