CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.287.1490
Functional Family Putative phosphatidylinositol 3-kinase regulatory subunit alpha

Enzyme Information

UniProtKB Entries (1)

P27986
P85A_HUMAN
Homo sapiens
Phosphatidylinositol 3-kinase regulatory subunit alpha

PDB Structure

PDB 5SXI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Identification of allosteric binding sites for PI3K alpha oncogenic mutant specific inhibitor design.
Miller, M.S., Maheshwari, S., McRobb, F.M., Kinzler, K.W., Amzel, L.M., Vogelstein, B., Gabelli, S.B.
Bioorg. Med. Chem.