CATH Classification

Domain Context

CATH Clusters

Superfamily Proprotein convertase subtilisin/kexin type 9
Functional Family Proprotein convertase subtilisin/kexin type 9

Enzyme Information

3.4.21.-
Serine endopeptidases.
based on mapping to UniProt Q8NBP7

UniProtKB Entries (1)

Q8NBP7
PCSK9_HUMAN
Homo sapiens
Proprotein convertase subtilisin/kexin type 9

PDB Structure

PDB 5OCA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Heparan sulfate proteoglycans present PCSK9 to the LDL receptor.
Gustafsen, C., Olsen, D., Vilstrup, J., Lund, S., Reinhardt, A., Wellner, N., Larsen, T., Andersen, C.B.F., Weyer, K., Li, J.P., Seeberger, P.H., Thirup, S., Madsen, P., Glerup, S.
Nat Commun
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