CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.60 | Sandwich | |
2.60.40 | Immunoglobulin-like | |
2.60.40.10 | Immunoglobulins |
Domain Context
CATH Clusters
Superfamily | Immunoglobulins |
Functional Family | Immunoglobulin heavy constant gamma 1 |
Enzyme Information
UniProtKB Entries (1)
P04626 |
ERBB2_HUMAN
Homo sapiens
Receptor tyrosine-protein kinase erbB-2
|
PDB Structure
PDB | 5O4G |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade.
Cancer Cell
|