CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.20 | Up-down Bundle | |
1.20.920 | Histone Acetyltransferase; Chain A | |
1.20.920.10 | Bromodomain-like |
Domain Context
CATH Clusters
Superfamily | Bromodomain-like |
Functional Family | Bromodomain-containing protein 2 |
Enzyme Information
UniProtKB Entries (1)
P25440 |
BRD2_HUMAN
Homo sapiens
Bromodomain-containing protein 2
|
PDB Structure
PDB | 5O3A |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Optimization of a "bump-and-hole" approach to allele-selective BET bromodomain inhibition.
Chem Sci
|