CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family galactocerebrosidase precursor

Enzyme Information

3.2.1.46
Galactosylceramidase.
based on mapping to UniProt P54818
D-galactosyl-N-acylsphingosine + H(2)O = D-galactose + N-acylsphingosine.
-!- Cf. EC 3.2.1.62.

UniProtKB Entries (1)

Q61207
SAP_MOUSE
Mus musculus
Prosaposin

PDB Structure

PDB 5NXB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The mechanism of glycosphingolipid degradation revealed by a GALC-SapA complex structure.
Hill, C.H., Cook, G.M., Spratley, S.J., Fawke, S., Graham, S.C., Deane, J.E.
Nat Commun