CATH Domain 5nneA01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Bromodomain-containing protein 4

Enzyme Information

UniProtKB Entries (1)

TOP2A_HUMAN

Homo sapiens

DNA topoisomerase 2-alpha

PDB Structure

PDB	5NNE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains. Lambert, J.P., Picaud, S., Fujisawa, T., Hou, H., Savitsky, P., Uuskula-Reimand, L., Gupta, G.D., Abdouni, H., Lin, Z.Y., Tucholska, M., Knight, J.D.R., Gonzalez-Badillo, B., St-Denis, N., Newman, J.A., Stucki, M., Pelletier, L., Bandeira, N., Wilson, M.D., Filippakopoulos, P., Gingras, A.C. Mol. Cell