CATH Domain 5n1xC00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.710	Potassium Channel Kv1.1; Chain A
	3.30.710.10	Potassium Channel Kv1.1; Chain A

Domain Context

CATH Clusters

Superfamily	Potassium Channel Kv1.1; Chain A
Functional Family	B-cell lymphoma 6 protein-like

Enzyme Information

UniProtKB Entries (1)

BCL6_HUMAN

Homo sapiens

B-cell lymphoma 6 protein

PDB Structure

PDB	5N1X
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors. McCoull, W., Abrams, R.D., Anderson, E., Blades, K., Barton, P., Box, M., Burgess, J., Byth, K., Cao, Q., Chuaqui, C., Carbajo, R.J., Cheung, T., Code, E., Ferguson, A.D., Fillery, S., Fuller, N.O., Gangl, E., Gao, N., Grist, M., Hargreaves, D., Howard, M.R., Hu, J., Kemmitt, P.D., Nelson, J.E., O'Connell, N., Prince, D.B., Raubo, P., Rawlins, P.B., Robb, G.R., Shi, J., Waring, M.J., Whittaker, D., Wylot, M., Zhu, X. J. Med. Chem.