CATH Classification

Domain Context

CATH Clusters

Superfamily L-arginine/glycine Amidinotransferase; Chain A
Functional Family Protein-arginine deiminase type-2

Enzyme Information

3.5.3.15
Protein-arginine deiminase.
based on mapping to UniProt Q9UM07
Protein L-arginine + H(2)O = protein L-citrulline + NH(3).
-!- Also acts on N-acyl-L-arginine and, more slowly, on L-arginine esters.

UniProtKB Entries (1)

Q9UM07
PADI4_HUMAN
Homo sapiens
Protein-arginine deiminase type-4

PDB Structure

PDB 5N1B
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Development of a Selective Inhibitor of Protein Arginine Deiminase 2.
Muth, A., Subramanian, V., Beaumont, E., Nagar, M., Kerry, P., McEwan, P., Srinath, H., Clancy, K., Parelkar, S., Thompson, P.R.
J. Med. Chem.
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