CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1240 | Phosphoglycerate mutase-like |
Domain Context
CATH Clusters
| Superfamily | Phosphoglycerate mutase-like |
| Functional Family | serine/threonine-protein phosphatase PGAM5, mitochondrial isoform X1 |
Enzyme Information
| 3.1.3.16 |
Protein-serine/threonine phosphatase.
based on mapping to UniProt Q96HS1
[a protein]-serine/threonine phosphate + H(2)O = [a protein]- serine/threonine + phosphate.
-!- A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48). -!- The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1).
|
UniProtKB Entries (1)
| Q96HS1 |
PGAM5_HUMAN
Homo sapiens
Serine/threonine-protein phosphatase PGAM5, mitochondrial
|
PDB Structure
| PDB | 5MUF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly.
Structure
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