CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.1490 | Dna Ligase; domain 1 | |
3.30.1490.20 | ATP-grasp fold, A domain |
Domain Context
CATH Clusters
Superfamily | ATP-grasp fold, A domain |
Functional Family |
Enzyme Information
UniProtKB Entries (3)
E1BQ43 |
E1BQ43_CHICK
Gallus gallus
Uncharacterized protein
|
P63043 |
STMN4_RAT
Rattus norvegicus
Stathmin-4
|
Q6B856 |
TBB2B_BOVIN
Bos taurus
Tubulin beta-2B chain
|
PDB Structure
PDB | 5M8D |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention.
Nat Commun
|