CATH Domain 5m8dB01

Superfamily	Tubulin/FtsZ, GTPase domain
Functional Family	Tubulin beta chain

E1BQ43	E1BQ43_CHICK Gallus gallus Uncharacterized protein
P63043	STMN4_RAT Rattus norvegicus Stathmin-4
Q6B856	TBB2B_BOVIN Bos taurus Tubulin beta-2B chain

PDB	5M8D
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention. Bohnacker, T., Prota, A.E., Beaufils, F., Burke, J.E., Melone, A., Inglis, A.J., Rageot, D., Sele, A.M., Cmiljanovic, V., Cmiljanovic, N., Bargsten, K., Aher, A., Akhmanova, A., Diaz, J.F., Fabbro, D., Zvelebil, M., Williams, R.L., Steinmetz, M.O., Wymann, M.P. Nat Commun