CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.750 | Elongin C; Chain C, domain 1 |
|
1.10.750.10 | von Hippel-Lindau disease tumour suppressor, alpha domain |
Domain Context
CATH Clusters
| Superfamily | von Hippel-Lindau disease tumour suppressor, alpha domain |
| Functional Family | von Hippel-Lindau disease tumor suppressor |
Enzyme Information
UniProtKB Entries (1)
| Q15370 |
ELOB_HUMAN
Homo sapiens
Elongin-B
|
PDB Structure
| PDB | 5LLI |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Potent and selective chemical probe of hypoxic signalling downstream of HIF-alpha hydroxylation via VHL inhibition.
Nat Commun
|