CATH Domain 5kseA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.150	DNA polymerase; domain 1
	1.10.150.20	5' to 3' exonuclease, C-terminal subdomain

Domain Context

CATH Clusters

Superfamily	5' to 3' exonuclease, C-terminal subdomain
Functional Family

Enzyme Information

3.1.-.-

Acting on ester bonds.

based on mapping to UniProt P39748

UniProtKB Entries (1)

FEN1_HUMAN

Homo sapiens

Flap endonuclease 1

PDB Structure

PDB	5KSE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability. Tsutakawa, S.E., Thompson, M.J., Arvai, A.S., Neil, A.J., Shaw, S.J., Algasaier, S.I., Kim, J.C., Finger, L.D., Jardine, E., Gotham, V.J.B., Sarker, A.H., Her, M.Z., Rashid, F., Hamdan, S.M., Mirkin, S.M., Grasby, J.A., Tainer, J.A. Nat Commun