CATH Classification

Domain Context

CATH Clusters

Superfamily 2.40.40.20
Functional Family Transitional endoplasmic reticulum ATPase

Enzyme Information

3.6.4.6
Vesicle-fusing ATPase.
based on mapping to UniProt P55072
ATP + H(2)O = ADP + phosphate.
-!- A large family of ATP-hydrolyzing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. -!- They belong to the AAA-type (ATPase associated with a variety of cell activities) ATPase superfamily. -!- They include peroxin, which apparently is involved in Zellweger's syndrome.

UniProtKB Entries (1)

Q9BQE4
SELS_HUMAN
Homo sapiens
Selenoprotein S

PDB Structure

PDB 5KIY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for nucleotide-modulated p97 association with the ER membrane.
Tang, W.K., Zhang, T., Ye, Y., Xia, D.
Cell Discov
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