CATH Domain 5kdhA01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Bromodomain-containing protein 4

Enzyme Information

UniProtKB Entries (1)

BRD4_HUMAN

Homo sapiens

Bromodomain-containing protein 4

PDB Structure

PDB	5KDH
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	BET Bromodomain Inhibitors with One-Step Synthesis Discovered from Virtual Screen. Ayoub, A.M., Hawk, L.M.L., Herzig, R.J., Jiang, J., Wisniewski, A.J., Gee, C.T., Zhao, P., Zhu, J.Y., Berndt, N., Offei-Addo, N.K., Scott, T.G., Qi, J., Bradner, J.E., Ward, T.R., Schonbrunn, E., Georg, G.I., Pomerantz, W.C.K. J. Med. Chem.