CATH Domain 5k7sA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.200	Peptidase S8/S53 domain

Domain Context

CATH Clusters

Superfamily	Peptidase S8/S53 domain
Functional Family	Proteinase K

Enzyme Information

3.4.21.64

Peptidase K.

based on mapping to UniProt P06873

Hydrolysis of keratin, and of other proteins with subtilisin-like specificity. Hydrolyzes peptide amides.

-!- From the mold Tritirachium album Limber. -!- Contains two disulfide bridges and one free Cys near the active site His. -!- Belongs to peptidase family S8. -!- Formerly EC 3.4.4.16 and EC 3.4.21.14.

UniProtKB Entries (1)

P06873

PRTK_PARAQ

Parengyodontium album

Proteinase K

PDB Structure

PDB	5K7S
External Links	PDBSum Proteopedia
Method	ELECTRON CRYSTALLOGRAPHY
Organism
Primary Citation	Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. de la Cruz, M.J., Hattne, J., Shi, D., Seidler, P., Rodriguez, J., Reyes, F.E., Sawaya, M.R., Cascio, D., Weiss, S.C., Kim, S.K., Hinck, C.S., Hinck, A.P., Calero, G., Eisenberg, D., Gonen, T. Nat. Methods