CATH Domain 5j8rA00

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.190	Protein-Tyrosine Phosphatase; Chain A
	3.90.190.10	Protein tyrosine phosphatase superfamily

Superfamily	Protein tyrosine phosphatase superfamily
Functional Family	Tyrosine-protein phosphatase non-receptor type 12

3.1.3.48

Protein-tyrosine-phosphatase.

based on mapping to UniProt Q05209

Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.

-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

PTN12_HUMAN

Homo sapiens

Tyrosine-protein phosphatase non-receptor type 12

PDB	5J8R
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure and substrate specificity of PTPN12. Li, H., Yang, F., Liu, C., Xiao, P., Xu, Y.F., Liang, Z.L., Liu, C., Wang, H.M., Wang, W.J., Zheng, W.S., Zhang, W., Ma, X.Y., He, D.F., Song, X.Y., Cui, F.A., Xu, Z.G., Yi, F., Sun, J.P., Yu, X. Cell Rep