CATH Domain 5iq7L02

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.10	Immunoglobulins

Domain Context

CATH Clusters

Superfamily	Immunoglobulins
Functional Family	Immunoglobulin kappa constant

Enzyme Information

UniProtKB Entries (1)

V9QIE5_9HIV1

Human immunodeficiency virus 1

Envelope glycoprotein gp160

PDB Structure

PDB	5IQ7
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design. Kwon, Y.D., Georgiev, I.S., Ofek, G., Zhang, B., Asokan, M., Bailer, R.T., Bao, A., Caruso, W., Chen, X., Choe, M., Druz, A., Ko, S.Y., Louder, M.K., McKee, K., O'Dell, S., Pegu, A., Rudicell, R.S., Shi, W., Wang, K., Yang, Y., Alger, M., Bender, M.F., Carlton, K., Cooper, J.W., Blinn, J., Eudailey, J., Lloyd, K., Parks, R., Alam, S.M., Haynes, B.F., Padte, N.N., Yu, J., Ho, D.D., Huang, J., Connors, M., Schwartz, R.M., Mascola, J.R., Kwong, P.D. J.Virol.