CATH Domain 5iq7L02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.10	Immunoglobulins

Domain Context

CATH Clusters

Superfamily	Immunoglobulins
Functional Family	Immunoglobulin kappa constant

Enzyme Information

UniProtKB Entries (1)

V9QIE5_9HIV1

Human immunodeficiency virus 1

Envelope glycoprotein gp160

PDB Structure

PDB	5IQ7
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design. Kwon, Y.D., Georgiev, I.S., Ofek, G., Zhang, B., Asokan, M., Bailer, R.T., Bao, A., Caruso, W., Chen, X., Choe, M., Druz, A., Ko, S.Y., Louder, M.K., McKee, K., O'Dell, S., Pegu, A., Rudicell, R.S., Shi, W., Wang, K., Yang, Y., Alger, M., Bender, M.F., Carlton, K., Cooper, J.W., Blinn, J., Eudailey, J., Lloyd, K., Parks, R., Alam, S.M., Haynes, B.F., Padte, N.N., Yu, J., Ho, D.D., Huang, J., Connors, M., Schwartz, R.M., Mascola, J.R., Kwong, P.D. J.Virol.