CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.40 | Barwin-like endoglucanases |
|
2.40.40.20 |
Domain Context
CATH Clusters
| Superfamily | 2.40.40.20 |
| Functional Family | Transitional endoplasmic reticulum ATPase |
Enzyme Information
| 3.6.4.6 |
Vesicle-fusing ATPase.
based on mapping to UniProt P55072
ATP + H(2)O = ADP + phosphate.
-!- A large family of ATP-hydrolyzing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. -!- They belong to the AAA-type (ATPase associated with a variety of cell activities) ATPase superfamily. -!- They include peroxin, which apparently is involved in Zellweger's syndrome.
|
UniProtKB Entries (1)
| Q9BZE9 |
ASPC1_HUMAN
Homo sapiens
Tether containing UBX domain for GLUT4
|
PDB Structure
| PDB | 5IFS |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
Nat Commun
|
