CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.472 | Cyclin A; domain 1 | |
1.10.472.10 | Cyclin-like |
Domain Context
CATH Clusters
Superfamily | Cyclin-like |
Functional Family | Putative cyclin-c |
Enzyme Information
UniProtKB Entries (1)
P49336 |
CDK8_HUMAN
Homo sapiens
Cyclin-dependent kinase 8
|
PDB Structure
PDB | 5IDN |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structure-Based Optimization of Potent, Selective, and Orally Bioavailable CDK8 Inhibitors Discovered by High-Throughput Screening.
J. Med. Chem.
|