1 keywords

CATH Domain 5hxbB04

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.150 DNA polymerase; domain 1
Homologous Superfamily 1.10.150.910  

Domain Context

CATH Clusters

Superfamily 1.10.150.910
Functional Family DNA damage-binding protein 1

Enzyme Information

UniProtKB Entries (1)

Q16531
DDB1_HUMAN
Homo sapiens
DNA damage-binding protein 1

PDB Structure

PDB 5HXB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase.
Matyskiela, M.E., Lu, G., Ito, T., Pagarigan, B., Lu, C.C., Miller, K., Fang, W., Wang, N.Y., Nguyen, D., Houston, J., Carmel, G., Tran, T., Riley, M., Nosaka, L., Lander, G.C., Gaidarova, S., Xu, S., Ruchelman, A.L., Handa, H., Carmichael, J., Daniel, T.O., Cathers, B.E., Lopez-Girona, A., Chamberlain, P.P.
Nature