CATH Classification

Domain Context

CATH Clusters

Superfamily Iron/manganese superoxide dismutase, C-terminal domain
Functional Family Superoxide dismutase [Mn], mitochondrial

Enzyme Information

1.15.1.1
Superoxide dismutase.
based on mapping to UniProt P04179
2 superoxide + 2 H(+) = O(2) + H(2)O(2).

UniProtKB Entries (1)

P04179
SODM_HUMAN
Homo sapiens
Superoxide dismutase [Mn], mitochondrial

PDB Structure

PDB 5GXO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A small molecule activator of SIRT3 promotes deacetylation and activation of manganese superoxide dismutase.
Lu, J., Zhang, H., Chen, X., Zou, Y., Li, J., Wang, L., Wu, M., Zang, J., Yu, Y., Zhuang, W., Xia, Q., Wang, J.
Free Radic. Biol. Med.