CATH Domain 5forA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.10140	Toll/interleukin-1 receptor homology (TIR) domain

Domain Context

CATH Clusters

Superfamily	Toll/interleukin-1 receptor homology (TIR) domain
Functional Family	phosphoinositide 3-kinase adapter protein 1

Enzyme Information

UniProtKB Entries (1)

BCAP_HUMAN

Homo sapiens

Phosphoinositide 3-kinase adapter protein 1

PDB Structure

PDB	5FOR
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of the Toll/Interleukin-1 Receptor (TIR) Domain of the B-cell Adaptor That Links Phosphoinositide Metabolism with the Negative Regulation of the Toll-like Receptor (TLR) Signalosome. Halabi, S., Sekine, E., Verstak, B., Gay, N.J., Moncrieffe, M.C. J. Biol. Chem.