CATH Domain 5entA04

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.1430	Multidrug efflux transporter AcrB pore domain

Domain Context

CATH Clusters

Superfamily	Multidrug efflux transporter AcrB pore domain
Functional Family	Efflux pump membrane transporter

Enzyme Information

UniProtKB Entries (1)

ACRB_ECOLI

Escherichia coli K-12

Multidrug efflux pump subunit AcrB

PDB Structure

PDB	5ENT
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives. Sjuts, H., Vargiu, A.V., Kwasny, S.M., Nguyen, S.T., Kim, H.S., Ding, X., Ornik, A.R., Ruggerone, P., Bowlin, T.L., Nikaido, H., Pos, K.M., Opperman, T.J. Proc.Natl.Acad.Sci.USA