CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.490 | Globin-like | |
1.10.490.10 | Globins |
Domain Context
CATH Clusters
Superfamily | Globins |
Functional Family | Hemoglobin subunit beta |
Enzyme Information
UniProtKB Entries (1)
P69905 |
HBA_HUMAN
Homo sapiens
Hemoglobin subunit alpha
|
PDB Structure
PDB | 5E83 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half-life in a murine model of sickle cell disease.
Br.J.Haematol.
|