CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1190 | UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase |
|
3.40.1190.20 | Ribokinase |
Domain Context
CATH Clusters
| Superfamily | 3.40.1190.20 |
| Functional Family |
Enzyme Information
| 2.7.1.50 |
Hydroxyethylthiazole kinase.
based on mapping to UniProt Q6GEY3
ATP + 4-methyl-5-(2-hydroxyethyl)thiazole = ADP + 4-methyl-5- (2-phosphonooxyethyl)thiazole.
|
UniProtKB Entries (1)
| Q6GEY3 |
THIM_STAAR
Staphylococcus aureus subsp. aureus MRSA252
Hydroxyethylthiazole kinase
|
PDB Structure
| PDB | 5COJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections.
Sci Rep
|
