CATH Domain 5cltC03

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.1180	Golgi alpha-mannosidase II

Domain Context

CATH Clusters

Superfamily	Golgi alpha-mannosidase II
Functional Family	1,4-alpha-glucan-branching enzyme

Enzyme Information

2.4.1.18

1,4-alpha-glucan branching enzyme.

based on mapping to UniProt Q04446

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.

-!- Converts amylose into amylopectin. -!- The description (official name) requires a qualification depending on the product, glycogen or amylopectin, e.g. glycogen branching enzyme, amylopectin branching enzyme. -!- The latter has frequently been termed Q-enzyme.

UniProtKB Entries (1)

Q04446

GLGB_HUMAN

Homo sapiens

1,4-alpha-glucan-branching enzyme

PDB Structure

PDB	5CLT
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of human glycogen branching enzyme (GBE1) in complex with acarbose Krojer, T., Froese, D.S., Goubin, S., Strain-Damerell, C., Mahajan, P., Burgess-Brown, N., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Yue, W., Structural Genomics Consortium (SGC) To be published