CATH Domain 5bt3A00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Histone acetyltransferase p300

Enzyme Information

2.3.1.48	Histone acetyltransferase. based on mapping to UniProt Q09472 Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine. -!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.
2.3.1.-	Transferring groups other than amino-acyl groups. based on mapping to UniProt Q09472

UniProtKB Entries (1)

EP300_HUMAN

Homo sapiens

Histone acetyltransferase p300

PDB Structure

PDB	5BT3
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of EP300 bromodomain in complex with a 3,5-dimethylisoxazol ligand Tallant, C., Hay, D., Krojer, T., Nunez-Alonso, G., Picaud, S., Newman, J.A., Fedorov, O., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Brennan, P.E., Knapp, S. To Be Published