1 keywords

CATH Domain 5ag9B01

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Gingipain R2

Enzyme Information

3.4.22.37
Gingipain R.
based on mapping to UniProt P95493
Hydrolysis of proteins and small molecule substrates, with a preference for Arg in P1.
-!- Strongly activated by glycine and stabilized by calcium. -!- Belongs to peptidase family C25.

UniProtKB Entries (1)

P95493
CPG2_PORGI
Porphyromonas gingivalis W83
Gingipain R2

PDB Structure

PDB 5AG9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The outer-membrane export signal of Porphyromonas gingivalis type IX secretion system (T9SS) is a conserved C-terminal beta-sandwich domain.
de Diego, I., Ksiazek, M., Mizgalska, D., Koneru, L., Golik, P., Szmigielski, B., Nowak, M., Nowakowska, Z., Potempa, B., Houston, J.A., Enghild, J.J., Thogersen, I.B., Gao, J., Kwan, A.H., Trewhella, J., Dubin, G., Gomis-Ruth, F.X., Nguyen, K.A., Potempa, J.
Sci Rep