CATH Domain 5a3fC02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.120	Four Helix Bundle (Hemerythrin (Met), subunit A)
	1.20.120.1240	Dynamin, middle domain

Domain Context

CATH Clusters

Superfamily	Dynamin, middle domain
Functional Family	dynamin-3 isoform X2

Enzyme Information

3.6.5.5

Dynamin GTPase.

based on mapping to UniProt Q9UQ16

GTP + H(2)O = GDP + phosphate.

-!- An enzyme with a molecular mass of about 100 kDa that is involved in endocytosis and is instrumental in pinching off membrane vesicles. -!- Formerly EC 3.6.1.50.

UniProtKB Entries (1)

Q9UQ16

DYN3_HUMAN

Homo sapiens

Dynamin-3

PDB Structure

PDB	5A3F
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structure of the Dynamin Tetramer Reubold, T.F., Faelber, K., Plattner, N., Posor, Y., Ketel, K., Curth, U., Schlegel, J., Anand, R., Manstein, D.J., Noe, F., Haucke, V., Daumke, O., Eschenburg, S. Nature