1 keywords

CATH Domain 4zopA04

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.1010 Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4
Homologous Superfamily 3.30.1010.10 Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4

Domain Context

CATH Clusters

Superfamily Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4
Functional Family Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit

Enzyme Information

UniProtKB Entries (0)

PDB Structure

PDB 4ZOP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Co-crystal Structure of the Lipid Kinase PI3K alpha with a selective phosphatidylinositol-3 kinase alpha inhibitorCo-crystal Structure of the Lipid Kinase PI3K alpha with a selective phosphatidylinositol-3 kinase alpha inhibitor
Fairhurst, R.A., Gerspacher, M., Imbach-Weese, P., Mah, R., Caravatti, G., Fuert, P., Fritsch, C., Schnell, C., Blanz, J., Blasco, F., Desrayaud, S., Guthy, D.A., Knapp, M.S., Arz, D., Wirth, J., Roehn-Carnemolla, E., Luu, V.H.
To Be Published