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1 keywords

CATH Domain 4wcvA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.1820 alpha/beta hydrolase

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family

Enzyme Information

3.8.1.5
Haloalkane dehalogenase.
based on mapping to UniProt P0A3G2
1-haloalkane + H(2)O = a primary alcohol + halide.
-!- Acts on a wide range of 1-haloalkanes, haloalcohols, haloalkenes and some haloaromatic compounds.

UniProtKB Entries (1)

P0A3G2
DHAA_RHORH
Rhodococcus rhodochrous
Haloalkane dehalogenase

PDB Structure

PDB 4WCV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Balancing the stability-activity trade-off by fine-tuning dehalogenase access tunnels
Liskova, V., Bednar, D., Prudnikova, T., Rezacova, P., Koudelakova, T., Sebestova, E., Kuta-Smatanova, I., Brezovsky, J., Chaloupkova, R., Damborsky, J.
Chemcatchem
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