CATH Domain 4wb9A02

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.309	Aldehyde Dehydrogenase; Chain A, domain 2
	3.40.309.10	Aldehyde Dehydrogenase; Chain A, domain 2

Domain Context

CATH Clusters

Superfamily	Aldehyde Dehydrogenase; Chain A, domain 2
Functional Family	Mitochondrial aldehyde dehydrogenase 2

Enzyme Information

1.2.1.36	Retinal dehydrogenase. based on mapping to UniProt P00352 Retinal + NAD(+) + H(2)O = retinoate + NADH. -!- Acts on both the 11-trans- and 13-cis-forms of retinal.
1.2.1.-	With NAD(+) or NADP(+) as acceptor. based on mapping to UniProt P00352

UniProtKB Entries (1)

AL1A1_HUMAN

Homo sapiens

Retinal dehydrogenase 1

PDB Structure

PDB	4WB9
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1. Morgan, C.A., Hurley, T.D. Chem.Biol.Interact.