CATH Domain 4usgA00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.31	Transcriptional Co-activator pc4; Chain A
	2.30.31.10	Transcriptional Coactivator Pc4; Chain A

Domain Context

CATH Clusters

Superfamily	Transcriptional Coactivator Pc4; Chain A
Functional Family	Activated RNA polymerase II transcriptional coactivator p15

Enzyme Information

UniProtKB Entries (1)

TCP4_HUMAN

Homo sapiens

Activated RNA polymerase II transcriptional coactivator p15

PDB Structure

PDB	4USG
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Substitution of Tryptophan 89 with Tyrosine Switches the DNA Binding Mode of Pc4. Huang, J., Zhao, Y., Liu, H., Huang, D., Cheng, X., Zhao, W., Taylor, I.A., Liu, J., Peng, Y.L. Sci.Rep.