CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.640 | Aspartate Aminotransferase; domain 2 |
|
3.40.640.10 | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Domain Context
CATH Clusters
| Superfamily | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
| Functional Family | Acetylornithine aminotransferase |
Enzyme Information
| 2.6.1.82 |
Putrescine--2-oxoglutarate transaminase.
based on mapping to UniProt P42588
Putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H(2)O.
-!- The enzymatic part of the reaction produces 4-aminobutanal that spontaneously cyclizes to form 1-pyrroline, which is a substrate for EC 1.2.1.19. -!- Cadaverine and spermidine can also act as substrates. -!- Forms part of the arginine catabolism pathway. -!- Cf. EC 2.6.1.113.
|
UniProtKB Entries (1)
| P42588 |
PAT_ECOLI
Escherichia coli K-12
Putrescine aminotransferase
|
PDB Structure
| PDB | 4UOY |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of Putrescine Aminotransferase from Escherichia Coli Provides Insights Into the Substrate Specificity Among Class III Aminotransferases.
Plos One
|
