CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.62 | Nef Regulatory Factor |
|
3.30.62.10 | Nef Regulatory Factor |
Domain Context
CATH Clusters
| Superfamily | Nef Regulatory Factor |
| Functional Family | Protein Nef |
Enzyme Information
UniProtKB Entries (2)
| P08631 |
HCK_HUMAN
Homo sapiens
Tyrosine-protein kinase HCK
|
| P03407 |
NEF_HV1A2
HIV-1 M:B_ARV2/SF2
Protein Nef
|
PDB Structure
| PDB | 4U5W |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Interaction with the Src Homology (SH3-SH2) Region of the Src-family Kinase Hck Structures the HIV-1 Nef Dimer for Kinase Activation and Effector Recruitment.
J.Biol.Chem.
|