CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.1910 |
Domain Context
CATH Clusters
| Superfamily | 2.60.40.1910 |
| Functional Family | Leucyl-cystinyl aminopeptidase |
Enzyme Information
| 3.4.11.3 |
Cystinyl aminopeptidase.
based on mapping to UniProt Q9UIQ6
Release of an N-terminal amino acid, Cys-|-Xaa-, in which the half- cystine residue is involved in a disulfide loop, notably in oxytocin or vasopressin. Hydrolysis rates on a range of aminoacyl arylamides exceed that for the cystinyl derivative, however.
-!- Belongs to peptidase family M1.
|
UniProtKB Entries (1)
| Q9UIQ6 |
LCAP_HUMAN
Homo sapiens
Leucyl-cystinyl aminopeptidase
|
PDB Structure
| PDB | 4PJ6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of human insulin-regulated aminopeptidase with specificity for cyclic peptides.
Protein Sci.
|