CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.1480 | Adenosylhomocysteinase-like |
Domain Context
CATH Clusters
Superfamily | Adenosylhomocysteinase-like |
Functional Family | Adenosylhomocysteinase |
Enzyme Information
3.3.1.1 |
Adenosylhomocysteinase.
based on mapping to UniProt P23526
S-adenosyl-L-homocysteine + H(2)O = L-homocysteine + adenosine.
-!- The NAD(+) cofactor appears to bring about a transient oxidation at C-3' of the 5'-deoxyadenosine residue, thus labilizing the thioether bond cf. EC 5.5.1.4.
|
UniProtKB Entries (1)
P23526 |
SAHH_HUMAN
Homo sapiens
Adenosylhomocysteinase
|
PDB Structure
PDB | 4PFJ |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Regulation of s-adenosylhomocysteine hydrolase by lysine acetylation.
J.Biol.Chem.
|