CATH Domain 4o1lA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.1110	Adenosine kinase, small domain
	3.30.1110.10

Domain Context

CATH Clusters

Superfamily	3.30.1110.10
Functional Family	Adenosine kinase a

Enzyme Information

2.7.1.20

Adenosine kinase.

based on mapping to UniProt P55263

ATP + adenosine = ADP + AMP.

-!- 2-aminoadenosine can also act as acceptor.

UniProtKB Entries (1)

ADK_HUMAN

Homo sapiens

Adenosine kinase

PDB Structure

PDB	4O1L
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides Snasel, J., Naus, P., Dostal, J., Hnizda, A., Fanfrlik, J., Brynda, J., Bourderioux, A., Dusek, M., Dvorakova, H., Stolarikova, J., Zabranska, H., Pohl, R., Konecny, P., Dzubak, P., Votruba, I., Hajduch, M., Rezacova, P., Veverka, V., Hocek, M., Pichova, I. J.Med.Chem.