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1 keywords

CATH Domain 4n9wA02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.2000 Glycogen Phosphorylase B;

Domain Context

CATH Clusters

Superfamily Glycogen Phosphorylase B;
Functional Family Phosphatidyl-myo-inositol mannosyltransferase

Enzyme Information

2.4.1.345
Phosphatidyl-myo-inositol alpha-mannosyltransferase.
based on mapping to UniProt A0QWG6
GDP-alpha-D-mannose + 1-phosphatidyl-1D-myo-inositol = GDP + 2-O-(alpha- D-mannosyl)-1-phosphatidyl-1D-myo-inositol.
-!- The enzyme, found in Corynebacteriales, is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIMs). -!- Formerly EC 2.4.1.57.

UniProtKB Entries (1)

A0QWG6
PIMA_MYCS2
Mycolicibacterium smegmatis MC2 155
Phosphatidyl-myo-inositol mannosyltransferase

PDB Structure

PDB 4N9W
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Secondary structure reshuffling modulates glycosyltransferase function at the membrane.
Giganti, D., Albesa-Jove, D., Urresti, S., Rodrigo-Unzueta, A., Martinez, M.A., Comino, N., Barilone, N., Bellinzoni, M., Chenal, A., Guerin, M.E., Alzari, P.M.
Nat.Chem.Biol.
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