CATH Domain 4mxwR02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.10	Ribbon
	2.10.50	Tumor Necrosis Factor Receptor, subunit A; domain 2
	2.10.50.10	Tumor Necrosis Factor Receptor, subunit A, domain 2

Domain Context

CATH Clusters

Superfamily	Tumor Necrosis Factor Receptor, subunit A, domain 2
Functional Family	Tumor necrosis factor receptor superfamily member 3

Enzyme Information

UniProtKB Entries (1)

TNFB_HUMAN

Homo sapiens

Lymphotoxin-alpha

PDB Structure

PDB	4MXW
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Dimerization of LT beta R by LT alpha 1 beta 2 is necessary and sufficient for signal transduction. Sudhamsu, J., Yin, J., Chiang, E.Y., Starovasnik, M.A., Grogan, J.L., Hymowitz, S.G. Proc.Natl.Acad.Sci.USA