CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1820 | alpha/beta hydrolase |
Domain Context
CATH Clusters
| Superfamily | alpha/beta hydrolase |
| Functional Family | Carboxypeptidase |
Enzyme Information
| 3.4.16.5 |
Carboxypeptidase C.
based on mapping to UniProt P10619
Release of a C-terminal amino acid with broad specificity.
-!- Carboxypeptidases of broad specificity with optimum pH 4.5-6.0, inhibited by the action of diisopropyl fluorophosphate, and sensitive to thiol-blocking reagents. -!- This enzyme is probably also identical to lysosomal tyrosine carboxypeptidase. -!- Belongs to peptidase family S10. -!- Formerly EC 3.4.12.1, EC 3.4.12.12, EC 3.4.16.1, EC 3.4.16.3 and EC 3.4.21.13.
|
UniProtKB Entries (1)
| P10619 |
PPGB_HUMAN
Homo sapiens
Lysosomal protective protein
|
PDB Structure
| PDB | 4MWS |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Proteolytic activation of human cathepsin A.
J.Biol.Chem.
|
