CATH Domain 4mhxA01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.720	Alkaline Phosphatase, subunit A
	3.40.720.10	Alkaline Phosphatase, subunit A

Domain Context

CATH Clusters

Superfamily	Alkaline Phosphatase, subunit A
Functional Family	N-sulphoglucosamine sulphohydrolase

Enzyme Information

3.10.1.1

N-sulfoglucosamine sulfohydrolase.

based on mapping to UniProt P51688

N-sulfo-D-glucosamine + H(2)O = D-glucosamine + sulfate.

UniProtKB Entries (1)

SPHM_HUMAN

Homo sapiens

N-sulphoglucosamine sulphohydrolase

PDB Structure

PDB	4MHX
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of sulfamidase provides insight into the molecular pathology of mucopolysaccharidosis IIIA. Sidhu, N.S., Schreiber, K., Propper, K., Becker, S., Uson, I., Sheldrick, G.M., Gartner, J., Kratzner, R., Steinfeld, R. Acta Crystallogr.,Sect.D