CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.20 | Ubiquitin-like (UB roll) |
|
3.10.20.90 | Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 |
| Functional Family | Polyubiquitin-C |
Enzyme Information
UniProtKB Entries (1)
| P49427 |
UB2R1_HUMAN
Homo sapiens
Ubiquitin-conjugating enzyme E2 R1
|
PDB Structure
| PDB | 4MDK |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin.
Nat.Chem.Biol.
|