CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.2020 |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.2020 |
| Functional Family | Ribose-phosphate pyrophosphokinase 1 |
Enzyme Information
| 2.7.6.1 |
Ribose-phosphate diphosphokinase.
based on mapping to UniProt P60891
ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- dATP can also act as donor.
|
UniProtKB Entries (1)
| P60891 |
PRPS1_HUMAN
Homo sapiens
Ribose-phosphate pyrophosphokinase 1
|
PDB Structure
| PDB | 4LZO |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations
Plos One
|
