CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleic acid-binding proteins
Functional Family Replication protein A subunit

Enzyme Information

UniProtKB Entries (1)

P27694
RFA1_HUMAN
Homo sapiens
Replication protein A 70 kDa DNA-binding subunit

PDB Structure

PDB 4LUO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of a potent inhibitor of replication protein a protein-protein interactions using a fragment-linking approach.
Frank, A.O., Feldkamp, M.D., Kennedy, J.P., Waterson, A.G., Pelz, N.F., Patrone, J.D., Vangamudi, B., Camper, D.V., Rossanese, O.W., Chazin, W.J., Fesik, S.W.
J.Med.Chem.