1 keywords

CATH Domain 4lcdF00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.10 Roll
Topology 3.10.20 Ubiquitin-like (UB roll)
Homologous Superfamily 3.10.20.90 Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Domain Context

CATH Clusters

Superfamily Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Functional Family Polyubiquitin-C

Enzyme Information

UniProtKB Entries (2)

P0CG48
UBC_HUMAN
Homo sapiens
Polyubiquitin-C
P39940
RSP5_YEAST
Saccharomyces cerevisiae S288C
E3 ubiquitin-protein ligase RSP5

PDB Structure

PDB 4LCD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3.
Kamadurai, H.B., Qiu, Y., Deng, A., Harrison, J.S., Macdonald, C., Actis, M., Rodrigues, P., Miller, D.J., Souphron, J., Lewis, S.M., Kurinov, I., Fujii, N., Hammel, M., Piper, R., Kuhlman, B., Schulman, B.A.
Elife