CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.10 | Immunoglobulins |
Domain Context
CATH Clusters
| Superfamily | Immunoglobulins |
| Functional Family | Immunoglobulin heavy constant gamma 1 |
Enzyme Information
UniProtKB Entries (1)
| P01859 |
IGHG2_HUMAN
Homo sapiens
Immunoglobulin heavy constant gamma 2
|
PDB Structure
| PDB | 4L4J |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations.
Methods
|
